No good trials show juices or cleanses remove toxins; any weight lost tends to come back.
What you hear: “Celery juice, juice cleanses and detox drinks flush toxins out of your body.”
A 2015 review found no randomised trials of commercial detox diets in humans and only a handful of small, flawed studies. The US NCCIH notes juice detoxes cause early weight loss from eating fewer calories, which tends to return once normal eating resumes. We found no human trials of celery juice for detoxing.
Take care: Unpasteurised juices can cause food poisoning, and high-oxalate green juices have caused kidney damage in susceptible people.
Your liver and kidneys do the detox work; fruit and vegetables are good to eat, but a cleanse adds no proven benefit.
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Not medical advice. General information from published studies, not a diagnosis or a treatment plan. Talk with your doctor before starting a supplement or changing a medicine, especially if you are pregnant, take other medicines or have a health condition.
Not proven: Not enough good human evidence yet, either way. We judge the claim as it is usually said online, not the habit itself. Trials assign people at random, so they can show cause; observed studies follow people and show a link, not proof. Last checked: October 2026.
no randomised controlled trials have been conducted to assess the effectiveness of commercial detox diets in humans.
juicing and "detox" diets can cause initial weight loss because of low intake of calories, but they tend to lead to weight gain once a person resumes a normal diet.
a case of acute oxalate nephropathy in a 65-year-old woman, temporally associated with the consumption of an oxalate-rich green smoothie juice "cleanse"
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